Advion BioSciences, Inc.

TriVersa NanoMate is the latest in chip-based technology from Advion that combines the strengths of liquid chromatography, mass spectrometry, fraction collection, and chip-based infusion in one integrated system. It allows researchers to obtain more information from their complex samples than with LC/MS alone. In liquid chromatography/mass spectrometry (LC/MS) fraction collection mode, the TriVersa NanoMate allows users to couple any conventional HPLC system to the TriVersa NanoMate for MS analysis. The effluent is split post column with a portion directed to a conventional LC/MS interface while the remainder of the split effluent is directed to collect at time segments into a multi-well plate. The chromatogram is thereby “cataloged” for future analysis. Following LC/MS, the researcher is able to select fractions of interest for more in-depth analysis via MS/MS. The process gives researchers the ability to spend more time analyzing complex portions of their samples without having to reinject.